Iatrogenic Cushing's syndrome induced by posaconazole.

نویسندگان

  • Benoit Pilmis
  • Hélène Coignard-Biehler
  • Vincent Jullien
  • Olivier Hermine
  • Philippe Touraine
  • Marc Lecuit
  • Olivier Lortholary
چکیده

Iatrogenic Cushing's syndrome is an undesirable outcome of glucocorticoids treatment. It can be increased by pharmacologic interactions. Glucocorticoid therapy, given in association with ritonavir, and some azole treatments are causes of iatrogenic Cushing's syndrome. We present a patient with common-variable immunodeficiency who received 7 years of itraconazole therapy for bronchial colonization with Aspergillus in combination with inhaled fluticasone without any Cushingoid symptoms. After a switch to posaconazole, the patient developed Cushingoid symptoms.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 57 11  شماره 

صفحات  -

تاریخ انتشار 2013